ALL PUBLICATIONS

Tammela T, Sanchez-Rivera FJ, Cetinbas NM, Wu K, Joshi NS, et al. A Wnt-producing niche drives proliferative potential and progression in lung adenocarcinoma. Nature. 2017 May 18;545(7654):355-359. PubMed PMID: 28489818.

Xin G, Schauder DM, Jing W, Jiang A, Joshi NS, et al. Pathogen boosted adoptive cell transfer immunotherapy to treat solid tumors. Proc Natl Acad Sci U S A. 2017 Jan 24;114(4):740-745. PubMed PMID: 28069963; PubMed Central PMCID: PMC5278465.

Adams NM, O'Sullivan TE, Geary CD, Karo JM, Amezquita RA, et al. NK Cell Responses Redefine Immunological Memory. J Immunol. 2016 Oct 15;197(8):2963-2970. PubMed PMID: 27824591; NIHMSID: NIHMS800172; PubMed Central PMCID: PMC5108457.

Akama-Garren EH*, Joshi NS*, Tammela T, Chang GP, Wagner BL, et al. A Modular Assembly Platform for Rapid Generation of DNA Constructs. Sci Rep. 2016 Feb 18;6:16836. PubMed PMID: 26887506; PubMed Central PMCID: PMC4757859.

Dominguez CX, Amezquita RA, Guan T, Marshall HD, Joshi NS, et al. The transcription factors ZEB2 and T-bet cooperate to program cytotoxic T cell terminal differentiation in response to LCMV viral infection. J Exp Med. 2015 Nov 16;212(12):2041-56. PubMed PMID: 26503446; PubMed Central PMCID: PMC4647261.

Joshi NS, Akama-Garren EH, Lu Y, Lee DY, Chang GP, et al. Regulatory T Cells in Tumor-Associated Tertiary Lymphoid Structures Suppress Anti-tumor T Cell Responses. Immunity. 2015 Sep 15;43(3):579-90. PubMed PMID: 26341400; NIHMSID: NIHMS769682; PubMed Central PMCID: PMC4826619. 

Sánchez-Rivera FJ, Papagiannakopoulos T, Romero R, Tammela T, Bauer MR, et al. Rapid modelling of cooperating genetic events in cancer through somatic genome editing. Nature. 2014 Dec 18;516(7531):428-31. PubMed PMID: 25337879; NIHMSID: NIHMS633102; PubMed Central PMCID: PMC4292871.

Xue W, Chen S, Yin H, Tammela T, Papagiannakopoulos T, et al. CRISPR-mediated direct mutation of cancer genes in the mouse liver. Nature. 2014 Oct 16;514(7522):380-4. PubMed PMID: 25119044; NIHMSID: NIHMS606316; PubMed Central PMCID: PMC4199937.

Cui W, Joshi NS, Liu Y, Meng H, Kleinstein SH, et al. TLR4 ligands lipopolysaccharide and monophosphoryl lipid a differentially regulate effector and memory CD8+ T Cell differentiation. J Immunol. 2014 May 1;192(9):4221-32. PubMed PMID: 24659688; NIHMSID: NIHMS570384; PubMed Central PMCID: PMC4071140.

Drake A, Joshi NS, Szeto GL, Zhu E, Eisen HN, et al. Koch Institute Symposium on Cancer Immunology and Immunotherapy. Cancer Immunol Res. 2013 Oct;1:217-222. PubMed PMID: 24466562; NIHMSID: NIHMS525722; PubMed Central PMCID: PMC3897860.

Joshi NS, Jacks T. Immunology Guilty by association. Science. 2013 Mar 8;339(6124):1160-1. PubMed PMID: 23471395.

Joshi NS, Cui W, Dominguez CX, Chen JH, Hand TW, et al. Increased numbers of preexisting memory CD8 T cells and decreased T-bet expression can restrain terminal differentiation of secondary effector and memory CD8 T cells. J Immunol. 2011 Oct 15;187(8):4068-76. PubMed PMID: 21930973; NIHMSID: NIHMS319679; PubMed Central PMCID: PMC3991478. 

Jung YW, Rutishauser RL, Joshi NS, Haberman AM, Kaech SM. Differential localization of effector and memory CD8 T cell subsets in lymphoid organs during acute viral infection. J Immunol. 2010 Nov 1;185(9):5315-25. PubMed PMID: 20921525; NIHMSID: NIHMS343065; PubMed Central PMCID: PMC4267692.

Hand TW, Cui W, Jung YW, Sefik E, Joshi NS, et al. Differential effects of STAT5 and PI3K/AKT signaling on effector and memory CD8 T-cell survival. Proc Natl Acad Sci U S A. 2010 Sep 21;107(38):16601-6. PubMed PMID: 20823247; PubMed Central PMCID: PMC2944719.

Hinson ER*, Joshi NS*, Chen JH, Rahner C, Jung YW, et al. Viperin is highly induced in neutrophils and macrophages during acute and chronic lymphocytic choriomeningitis virus infection. J Immunol. 2010 May 15;184(10):5723-31. PubMed PMID: 20410488; NIHMSID: NIHMS526962; PubMed Central PMCID: PMC3883313.

Cui W, Joshi NS, Jiang A, Kaech SM. Effects of Signal 3 during CD8 T cell priming: Bystander production of IL-12 enhances effector T cell expansion but promotes terminal differentiation. Vaccine. 2009 Mar 26;27(15):2177-87. PubMed PMID: 19201385; NIHMSID: NIHMS103971; PubMed Central PMCID: PMC2803112.

Chandele A, Joshi NS, Zhu J, Paul WE, Leonard WJ, et al. Formation of IL-7Ralphahigh and IL-7Ralphalow CD8 T cells during infection is regulated by the opposing functions of GABPalpha and Gfi-1. J Immunol. 2008 Apr 15;180(8):5309-19. PubMed PMID: 18390712; NIHMSID: NIHMS144818; PubMed Central PMCID: PMC2792750.

Joshi NS, Kaech SM. Effector CD8 T cell development: a balancing act between memory cell potential and terminal differentiation. J Immunol. 2008 Feb 1;180(3):1309-15. PubMed PMID: 18209024.

Joshi NS, Cui W, Chandele A, Lee HK, Urso DR, et al. Inflammation directs memory precursor and short-lived effector CD8(+) T cell fates via the graded expression of T-bet transcription factor. Immunity. 2007 Aug;27(2):281-95. PubMed PMID: 17723218; NIHMSID: NIHMS29566; PubMed Central PMCID: PMC2034442. 

Tesar BM, Walker WE, Unternaehrer J, Joshi NS, Chandele A, et al. Murine [corrected] myeloid dendritic cell-dependent toll-like receptor immunity is preserved with aging. Aging Cell. 2006 Dec;5(6):473-86. PubMed PMID: 17129212.

Martomo SA, Fu D, Yang WW, Joshi NS, Gearhart PJ. Deoxyuridine is generated preferentially in the nontranscribed strand of DNA from cells expressing activation-induced cytidine deaminase. J Immunol. 2005 Jun 15;174(12):7787-91. PubMed PMID: 15944282.

Henry RM, Hoppe AD, Joshi N, Swanson JA. The uniformity of phagosome maturation in macrophages. J Cell Biol. 2004 Jan 19;164(2):185-94. PubMed PMID: 14718518; PubMed Central PMCID: PMC2172341.